Frameless Navigation

What different options are there for navigation in brain surgery? [28,29, 31,32]

What is the accuracy of frame based vs. frame less navigation? (try to find a more recent paper than [30]) [35]

Frameless radiosurgery [33]

Frameless stereotactic surgery [36] is based on fiducial to register pre-operative images to patient space. How to best place the fiducials? [37]

Non-invasive patient tracker - electromagnetic tracker based [38]

Intraoperative photograph showing the skull-mounted tracker (Stryker) before ... Image resource: Frameless and Maskless Stereotactic Navigation with a Skull-Mounted Tracker [34]

 

 

Surgical Simulators

Surgical training (education):

  • Systematic assessment of surgical simulation training in neurosurgical context has been conducted by [21]; Cadaver, physical and haptic/computerized simulations all improved students' skills, but computer based simulations gave the least benefit for them (63.8%). Are there other studies supporting or refuting this?
  • AR and VR for surgical training [9]

Surgical Rehearsal Platforms:

  • Pre-operative imaging is used for presurgical planning and rehearsal for example in Dextroscope - measurable benefit due to interpatient variability [24]
  • Specific example for brain tumor surgery? [25, 26]

What parts does a simulator usually include? [22,24]

  • Volume rendering / graphics - algorithms for creating and displaying 3D anatomical models
  • Model response / tissue deformation - 3D models need to react to user interaction
  • Haptics - usually transmitted to the user through an external haptic interface

Model building

  • (non algorithmic) patient specific and/or in larger amounts - 3D printing with multiple materials [23]
  • (algorithmic) anatomical modeling of geometry, visual appearance and biomechanical behaviour of anatomy and tissue [24]

Examples for simulators:

  • NeuroTouch / NeuroVR [26]
  • Patient specific simulator like in other disciplines [27] available?

EDEN2020

EDEN2020 is an EU funded project that combines a lot of these technical aspects. Core features include:

  • develop a stearable catheter
  • robotic control of stearable catheter
  • measure brainshift with high accuracy and precision
  • Computational fluid dynamics

  • Mechanical modelling of brain tissue

What else? Are there other (EU) projects to boost technological evolution?

Bibliography

[1] Jolesz, Ferenc, ed. Intraoperative imaging and image-guided therapy. Springer Science & Business Media, 2014.

[2] Jolesz FA. Intraoperative Imaging in Neurosurgery: Where Will the Future Take Us? Acta neurochirurgica Supplement. 2011;109:21-25. doi:10.1007/978-3-211-99651-5_4.

[3] Li, Yiping, et al. "Intraoperative fluorescence-guided resection of high-grade gliomas: a comparison of the present techniques and evolution of future strategies." World neurosurgery 82.1 (2014): 175-185.

[4] Zausinger, Stefan, et al. "Intraoperative CT in neurosurgery." Intraoperative Imaging and Image-Guided Therapy. Springer New York, 2014. 529-536.

[5] Peters, Terry M., and Cristian A. Linte. "Image-guided interventions and computer-integrated therapy: Quo vadis?." (2016): 56-63.

[6] Guha, Daipayan, et al. "Augmented Reality in Neurosurgery: A Review of Current Concepts and Emerging Applications." Canadian Journal of Neurological Sciences 44.3 (2017): 235-245.

[7] Meola, Antonio, et al. "Augmented reality in neurosurgery: a systematic review." Neurosurgical review (2016): 1-12.

[8] Sun, Guo-chen, et al. "Impact of Virtual and Augmented Reality Based on Intraoperative Magnetic Resonance Imaging and Functional Neuronavigation in Glioma Surgery Involving Eloquent Areas." World Neurosurgery 96 (2016): 375-382.

[9] Pelargos, Panayiotis E., et al. "Utilizing virtual and augmented reality for educational and clinical enhancements in neurosurgery." Journal of Clinical Neuroscience 35 (2017): 1-4.

[10] Choudhri, A. F., et al. "3T intraoperative MRI for management of pediatric CNS neoplasms." American Journal of Neuroradiology 35.12 (2014): 2382-2387.

[11] Coburger, Jan, et al. "Low-grade glioma surgery in intraoperative magnetic resonance imaging: results of a multicenter retrospective assessment of the German study group for intraoperative magnetic resonance imaging." Neurosurgery 78.6 (2016): 775-786.

[12] Fahlbusch, R. & Samii, A. "Editorial: Intraoperative MRI" Neurosurgical Focus, 2016, 40, E3

[13] Moiyadi, Aliasgar V., and Prakash Shetty. "Direct navigated 3D ultrasound for resection of brain tumors: a useful tool for intraoperative image guidance." Neurosurgical focus 40.3 (2016): E5.

[14] Madhavan, Karthik, et al. "Augmented-reality integrated robotics in neurosurgery: are we there yet?." Neurosurgical Focus 42.5 (2017): E3.

[15] Doulgeris, James J., S. MSME, and A. MSBE. "Robotics in neurosurgery: evolution, current challenges, and compromises." Cancer Control 22.3 (2015): 352-360.

[16] Faria, Carlos, et al. "A Simple Control Approach for Stereotactic Neurosurgery Using a Robotic Manipulator." CONTROLO 2016. Springer International Publishing, 2017. 397-408.

[17] Fei, Baowei, et al. "The safety issues of medical robotics." Reliability Engineering & System Safety 73.2 (2001): 183-192.

[18] Mattei, Tobias A., et al. "Current state-of-the-art and future perspectives of robotic technology in neurosurgery." Neurosurgical review 37.3 (2014): 357-366.

[19] Faria, Carlos, et al. "Review of robotic technology for stereotactic neurosurgery." IEEE reviews in biomedical engineering 8 (2015): 125-137.

[20] Sekhar, Laligam N., et al. "Commentary: virtual reality and robotics in neurosurgery." Neurosurgery 72 (2013): A1-A6.

[21] Gasco, Jaime, et al. "Neurosurgery simulation in residency training: feasibility, cost, and educational benefit." Neurosurgery 73 (2013): S39-S45.

[22] Malone, Hani R., et al. "Simulation in neurosurgery: a review of computer-based simulation environments and their surgical applications." Neurosurgery 67.4 (2010): 1105-1116.

[23] Waran, Vicknes, et al. "Utility of multimaterial 3D printers in creating models with pathological entities to enhance the training experience of neurosurgeons: technical note." Journal of neurosurgery 120.2 (2014): 489-492.

[24] Chan, Sonny, et al. "Virtual reality simulation in neurosurgery: technologies and evolution." Neurosurgery 72 (2013): A154-A164.

[25] Azarnoush, Hamed, et al. "Neurosurgical virtual reality simulation metrics to assess psychomotor skills during brain tumor resection." International journal of computer assisted radiology and surgery 10.5 (2015): 603-618.

[26] Delorme, Sébastien, et al. "NeuroTouch: a physics-based virtual simulator for cranial microneurosurgery training." Neurosurgery 71 (2012): ons32-ons42.

[27] Willaert, Willem IM, et al. "Recent advancements in medical simulation: patient-specific virtual reality simulation." World journal of surgery 36.7 (2012): 1703-1712.

[28] Abrishamkar, Saeid, et al. "A new system for neuronavigation and stereotactic biopsy pantograph stereotactic localization and guidance system." Journal of surgical technique and case report 3.2 (2011).

[29] Orringer, Daniel A., Alexandra Golby, and Ferenc Jolesz. "Neuronavigation in the surgical management of brain tumors: current and future trends." Expert review of medical devices 9.5 (2012): 491-500.

[30] Bjartmarz, Hjalmar, and Stig Rehncrona. "Comparison of accuracy and precision between frame-based and frameless stereotactic navigation for deep brain stimulation electrode implantation." Stereotactic and functional neurosurgery 85.5 (2007): 235-242.

[31] Safaee, Michael, John Burke, and Michael W. McDermott. "Techniques for the Application of Stereotactic Head Frames Based on a 25-Year Experience." Cureus 8.3 (2016).

[32] https://cdn.intechopen.com/pdfs-wm/30676.pdf

[33] Bilger, A. C., et al. "P14. 20 Local control an overall survival after frameless LINAC radiosurgery: a single center experience." Neuro-Oncology 19.suppl_3 (2017): iii106-iii106.

[34] Fanous, Andrew A., et al. "Frameless and Maskless Stereotactic Navigation with a Skull-Mounted Tracker." World Neurosurgery (2017).

[35] Bardon, J., et al. "EP 46. Accuracy of deep brain stimulation electrodes placement using frameless system–Nexframe©." Clinical Neurophysiology 127.9 (2016): e195.

[36] White, Tim, et al. "Frameless Stereotactic Insertion of Viewsite Brain Access System with Microscope-Mounted Tracking Device for Resection of Deep Brain Lesions: Technical Report." Cureus 9.2 (2017).

[37] Smith, Timothy R., et al. "Impact of fiducial arrangement and registration sequence on target accuracy using a phantom frameless stereotactic navigation model." Journal of Clinical Neuroscience 21.11 (2014): 1976-1980.

[38] Morsy, Ahmed A., and Wai Hoe Ng. "Awake craniotomy using electromagnetic navigation technology without rigid pin fixation." Journal of Clinical Neuroscience 22.11 (2015): 1827-1829.

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